EDK
Editome Disease Knowledgebase
Multiple Myeloma
| Disease name | Multiple Myeloma |
|---|---|
| Classfication | Cancer |
| Related Enzyme(s) | |
| EFO | - |
| DOID | 9538 |
| OMIM | |
| NCI | |
| Definition | A myeloid neoplasm that is located in the plasma cells in bone marrow. |
| Gene symbol | Species | Enzyme | Editing site(s) | Editing Type | PMID | RADAR | REDIportal | Description |
|---|---|---|---|---|---|---|---|---|
| GLI1 | Human | ADAR1 | 1 | A-to-I | ADAR1 enhances Alu dependent editing and transcriptional activity of GLI1, Notably, GLI1 transcript editing rates were significantly higher in relapsed multiple myeloma than age-matched controls |